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Date of Award

9-20-2010

Document Type

Dissertation

Degree Name

Doctor of Philosophy (PhD)

Department

Applied Science

First Advisor

Mitchell Keith Hudson

Abstract

Magnetoencephalography (MEG) is widely used to study magnetic fields generated by the electrical activity of the human brain and can also be applied for fetal neurological health assessment. The fetal MEG (fMEG) signals are often contaminated with other bio-magnetic signals such as fetal breathing movement (FBM), which acts as an interfering factor for fetal neurological signals. This study was carried out to identify the bio-magnetic signals pertinent to the FBM. The fMEG signals were captured using superconducting quantum interference devices (SQUIDs) and the FBMs were recorded by an ultrasound-based video technique. The simultaneous recording is challenging since SQUIDs are extremely sensitive to magnetic signals and highly susceptible to interference from electronic equipment. The results showed the existence of a distinctive FBM signal pattern similar to a sinusoidal wave in fMEG data. The magnetic field distribution during breathing indicated that the signals were located in the proximity of the fetal heart. Further, this study proved that simultaneous operation of ultrasound and SQUID is possible for the FBM observations.

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