Date of Award

5-25-2021

Document Type

Dissertation

Degree Name

Doctor of Philosophy (PhD)

Department

Systems Engineering

First Advisor

Xian Liu

Abstract

The vibrant subject of blood banking and blood distribution is addressed where lateral resupply of blood products is allowed. In this research, a blood supply chain network design (BSCND) consisting of four conventional levels each of which corresponding to one entity in the real world is comprehensively studied: donors, blood collection facilities, blood centers, and hospitals. Two important properties are considered within the blood supply chain network (BSCN): ABO-Rh factors and shelf lives of blood products. Moreover, an integrated inventory system for sharing hospitals’ inventory levels is designed to investigate the two performance indicators of the network in terms of cross-matching and outdated units. This type of inventory system is known as “Lateral Resupply” permitting a hospital to obtain the supply from the rest of hospitals’ inventories in the absence of the required product at the blood bank and its excess in any hospital. During the COVID-19 pandemic, the American Red Cross says that there is an enduring need for blood and blood product donation. Additionally, the U.S. Food & Drug Administration indicates a pressing need for blood. Overall, the problems stated in this dissertation are novel yet practical and instances are discussed under normal and critical circumstances. However, conventional optimization methods are employed to tackle them.

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